3-dimensional silk hydroxyapatite compositions

Details 3-dimensional silk hydroxyapatite compositions 3-dimensional silk hydroxyapatite compositions

A - Human Necessities

61

L

A61L 27/14 (2006.01) A61F 2/28 (2006.01) A61L 27/12 (2006.01) A61L 27/54 (2006.01)

Patent

CA 2713251

Described herein are methods and compositions comprising a mixture of silk polymer and hydroxyapatite. The methods described herein can be used to prepare a mixture of silk polymer and hydroxyapatite and further provide mixtures that can be molded into a desired shape. Also encompassed herein are compositions comprising a mixture of silk polymer and hydroxyapatite having a desired shape, which can further be implanted, for example, to facilitate bone healing or tooth structure or support. Such compositions can also include agents, such as therapeutic agents, or cells.

La présente invention a trait à des procédés et des compositions comprenant un mélange d'un polymère de soie et d'une hydroxyapatite. Les procédés décrits ici peuvent être utilisés pour la préparation d'un mélange d'un polymère de soie et d'une hydroxyapatite et permettent d'obtenir, en outre, des mélanges qui peuvent être moulés selon la forme souhaitée. L'invention a également trait à des compositions comprenant un mélange d'un polymère de soie et d'une hydroxyapatite de la forme souhaitée, qui peuvent, en outre, être implantées, par exemple pour faciliter la consolidation osseuse, en tant que structure dentaire ou de support. Lesdites compositions peuvent également comprendre des agents, par exemple des agents thérapeutiques, ou des cellules.

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