4-(4-imidazolyl) piperidines substituted at position 1,...

Details 4-(4-imidazolyl) piperidines substituted at position 1,... 4-(4-imidazolyl) piperidines substituted at position 1,...

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2058563

ABSTRACT New 4-(4-imidazolyl)piperidines substituted at position 1, their preparation and also their therapeutic applica- tions. The compounds correspond to the general formula Image in which R1 represents a hydrogen atom or a group -COR2, in which R2 represents a benzene ring, cyclopentylmethyl, cyclohexylmethyl, cyclopentylethyl or cyclohexylethyl groups or cyclopentylamine, cyclohexylamine or phenyl- amine, chlorophenylamine or dichlorophenylamine groups; R represents a hydrogen atom or a group COR3, in which R3 represents an aliphatic group, a cyclane or benzene ring- system, a group (CH2)nR4, a group -CH=CHR8 or a secondary amine group -NH(CH2)nR9; R also represents a hydroxy- alkenyl group: Image

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