4-4(methylpiperazin-1-ylmethyl)-n-[4-methyl-3-(pyridin-3-yl)...

Details 4-4(methylpiperazin-1-ylmethyl)-n-[4-methyl-3-(pyridin-3-yl)... 4-4(methylpiperazin-1-ylmethyl)-n-[4-methyl-3-(pyridin-3-yl)...

A - Human Necessities

61

K

A61K 31/506 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2493000

The invention relates to the use of 4-(4-methylpiperazin-l-ylmethyl)-N-(4- methyl-3-(4-pyridin3-yl)pyrimidin-2-ylamino)phenyl]-benzamide or a pharmaceutically acceptable salt thereof for the treatment of mutated-RET kinase associated disease, especially mutated-RET kinase associated thyroid cancer.

L'invention concerne l'utilisation de 4-(4-méthylpipérazin-1-ylméthyl)-N-[4 méthyl-3-(4-pyridin-3yl)pyrimidin-2-ylamino)phényl] benzamide ou d'un sel pharmaceutiquement acceptable dudit composé pour le traitement d'une maladie associée à une kinase RET mutée, notamment le cancer de la thyroïde associé à une kinase RET mutée.

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