4,5-dihydro-4-oxo-pyrrolo [1,2-a] quinoxalinones] and...

Details 4,5-dihydro-4-oxo-pyrrolo [1,2-a] quinoxalinones] and... 4,5-dihydro-4-oxo-pyrrolo [1,2-a] quinoxalinones] and...

C - Chemistry, Metallurgy

07

D

C07D 471/14 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2104653

ABSTRACT OF THE DISCLOSURE The invention relates to pharmaceutically useful novel compounds of the formula Image I where the phenyl ring can also contain a nitrogen atom instead of a CH group, R1 is C2-C6-alkenyl, C2-C6-alkinyl, hydroxy, C1-C6-alkoxy, C3-C6-alkenyloxy, C3-C6-alkinyloxy, C2-C6-alkanoyloxy, benzoyloxy, morpholinocarbonyloxy, C1-C6-alkyloxycarbonyloxy, C1-C6-alkylaminocarbonyloxy, C1-C6-dialkylaminocarbonyloxy or the group -Alk-A, where Alk represents C1-C6-alkyl, C2-C6-hydroxyalkyl or C3-C6-cycloalkyl and the symbol A represents hydrogen or other substituents. R2, R3 and R4 represent various substituents, where R1 may also be hydrogen, when R2 is the group Image and R5 represents phenyl, C1-C4-alkoxyphenyl or diphenylmethyl and R3 and R4 are hydrogen and their salts. The invention also relates to a novel process for the preparation of starting materials for the compounds of Formula I.

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