4,6-disubstituted pyrimidines and their use as protein...

Details 4,6-disubstituted pyrimidines and their use as protein... 4,6-disubstituted pyrimidines and their use as protein...

C - Chemistry, Metallurgy

07

D

C07D 405/04 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2570552

The invention relates to novel pyrimidine derivatives of Formula (I), which are efficacious inhibitors of protein kinases, in particular of one or more isoforms of the protein kinase B/Akt.

L'invention concerne de nouveaux dérivés de pyrimidine représentés par la formule (I), constituant d'efficaces inhibiteurs des protéines kinases, en particulier d'une ou de plusieurs isoformes de la protéine kinase B/Akt.

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