4-amino-thieno[3,2-c]pyridine-7-carboxylic acid derivatives

Details 4-amino-thieno[3,2-c]pyridine-7-carboxylic acid derivatives 4-amino-thieno[3,2-c]pyridine-7-carboxylic acid derivatives

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/435 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2621830

The present invention relates to compounds of the formula (I-A) medicaments containing them and the use of these compounds as pharmaceutically active agents. The compounds exhibit activity as Raf kinase inhibitors and therefore may be useful for the treatment of diseases mediated by said kinases, especially as anticancer agents.

La présente invention concerne des composés de formule (I-A), des médicaments les contenant et l'emploi de ces composés au titre de principes pharmaceutiquement actifs. Les composés présentent une activité d'inhibiteurs de Raf kinase, et peuvent donc être employés dans le traitement de maladies faisant intervenir lesdites kinases, en particulier en tant qu'agents anticancéreux.

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