4-biarylyl-1-phenylazetidin-2-ones

Details 4-biarylyl-1-phenylazetidin-2-ones 4-biarylyl-1-phenylazetidin-2-ones

C - Chemistry, Metallurgy

07

D

C07D 205/08 (2006.01) A61K 31/397 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2545058

4-Biarylyl-1-phenylazetidin-2-ones useful for the treatment of hypercholesterolemia are disclosed. The compounds are of a general formula (I) in which formula (II) represents an aryl or heteroaryl residue, Ar represents an aryl residue; U is a two to six atom chain; and the R~s represent substituents.

L'invention porte sur des 4-biarylyl-1-phénylazétidin-2-ones servant au traitement de l'hypercholestérolémie. Ces composés présentent la formule générale (I) dans laquelle la formule (II) représente un résidu aryle ou hétéroaryle, Ar représente un résidu aryle, U représente une chaîne de 2 à 6 atomes, et les R représentent des substituants.

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