4'-deshydroxyepipodophyllotoxin glucosides: synthesis and use

Details 4'-deshydroxyepipodophyllotoxin glucosides: synthesis and use 4'-deshydroxyepipodophyllotoxin glucosides: synthesis and use

C - Chemistry, Metallurgy

07

H

167/185, 167/202

C07H 15/26 (2006.01) C07H 17/04 (2006.01)

Patent

CA 1317290

ABSTRACT Novel 4'-deshydroxyepipodophyllotoxin glucosides are provided as antitumor agents useful in inhibiting the growth of mammalian tumors. The invention also provides novel intermediates and processes for the.preparation of the 4'-deshydroxyepipodophyllotoxin glucoside end-products. A preferred em'oodiment is 4'-deshydroxyetoposide.

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