4-(hetero)aryl substituted indolinones

Details 4-(hetero)aryl substituted indolinones 4-(hetero)aryl substituted indolinones

C - Chemistry, Metallurgy

07

D

C07D 403/06 (2006.01) A61K 31/496 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 209/34 (2006.01) C07D 209/42 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 417/14 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2432114

The present invention relates to 4-arylindolinones of formula (I), as well as pharmaceutical compositions thereof, capable of modulating protein kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation. The present invention relates to methods for treating protein kinase related disorders. Formula (I) wherein: R1 is an optionally substituted aryl or heteroaryl substituent, R2-R5 are as in claim 1.

L'invention concerne des 4-arylindolinones, ainsi que des compositions pharmaceutiques de celles-ci, capables de moduler une transduction de signal de protéines kinases, de manière à réguler, moduler et/ou inhiber une prolifération cellulaire anormale. L'invention concerne également des méthodes de traitement de troubles relatifs aux protéines kinases.

Affiliated with

Also associated with

Rating

4-(hetero)aryl substituted indolinones does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 4-(hetero)aryl substituted indolinones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-(hetero)aryl substituted indolinones will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1618044