4-hydroxy-4-phenylpiperidine derivatives and pharmaceuticals...

Details 4-hydroxy-4-phenylpiperidine derivatives and pharmaceuticals... 4-hydroxy-4-phenylpiperidine derivatives and pharmaceuticals...

C - Chemistry, Metallurgy

07

D

C07D 211/52 (2006.01) A61K 31/451 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2324330

Described is a 4-hydroxy-4-phenylpiperidine derivative represented by the following formula (1): (see formula I) [wherein, R1 and R2 are the same or different and each independently represents a hydrogen atom, a lower alkyl, or the like, R3 represents a hydrogen atom or a group - (CR4R5)n-Y (in which, R4 and R5 each represents a hydrogen atom or a lower alkyl group, Y represents a group -COOR6, -CONR7R8, -OR9 or -OCOR10 (in which R6, R9 and R10 each independently represents a hydrogen atom, a lower alkyl group, or the like, R7 and R8 are the same or different and each independently represents a hydrogen atom, a lower alkyl group, or the like), and n stands for 1 to 6)], or salt thereof. The compound exhibits excellent peripheral analgesic action.

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