4-hydroxybutyric acid analogs

C - Chemistry – Metallurgy – 07 – B

Patent

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Details

C07B 59/00 (2006.01) C07C 59/01 (2006.01)

Patent

CA 2759251

This invention relates to novel derivatives of 4-hydroxybutyric acid and prodrugs thereof, and pharmaceutically acceptable salts of the foregoing. This invention also provides pharmaceutical compositions comprising a compound of this invention and the use of such compositions in methods of treating narcolepsy, fibromyalgia, other disorders or conditions that are beneficially treated by improving nocturnal sleep or by administering sodium oxybate.

La présente invention porte sur de nouveaux dérivés de l'acide 4-hydroxybutyrique et les promédicaments de ces dérivés, ainsi que sur des sels pharmaceutiquement acceptables de ces dérivés et promédicaments. La présente invention porte également sur des compositions pharmaceutiques comprenant un composé de l'invention, ainsi que sur l'utilisation de ces compositions dans des méthodes de traitement de la narcolepsie, de la fibromyalgie, d'autres troubles ou états pathologiques qui sont avantageusement traités par une amélioration du sommeil nocturne ou par administration d'oxybate de sodium.

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