4' substituted compounds having 5-ht6 receptor affinity

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/12 (2006.01) A61K 31/496 (2006.01) A61K 31/538 (2006.01) A61P 25/00 (2006.01) C07D 209/08 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 417/12 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2687132

The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I), wherein R1, R2, R5, R6, B, D, E, G, Q, x and n are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

La présente invention concerne des composés ayant une affinité pour le récepteur 5-HT6 qui répondent à la formule (I), où R1, R2, R5, R6, B, D, E, G, Q, x et n sont tels que définis ici. L'invention concerne également des procédés de préparation de tels composés, des compositions contenant de tels composés et des procédés d'utilisation de ceux-ci.

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