5-aminolevulinic acid and esters, in combination with...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/197 (2006.01) A61K 41/00 (2006.01)

Patent

CA 2454136

The method relates to the use of a photosensitizer selected from 5- aminolevulinic acid (5-ALA) and 5-ALA derivatives, and pharmaceutically acceptable salts thereof, in the manufacture of a medicament for use in treating a wound. Examples of wounds which may be treated in accordance with the invention include those resulting from non-physiological processes, e.g. from surgery or from physical injury, abrasions, lacerations, and wounds arising from a thermal injury (e.g. a burn or a wound arising from any cryo- based treatment). Ulcers, e.g. leg ulcers, venous ulcers and gastric ulcers, may also be successfully treated in accordance with the methods of the invention.

L'invention concerne l'utilisation d'un photosensibilisant sélectionné à partir de l'acide 5-aminolévulinique (5-ALA) et des dérivés de 5-ALA, ainsi que leurs sels pharmaceutiquement acceptables, dans la préparation d'un médicament utilisé dans le traitement d'une blessure. Parmi les blessures pouvant être traitées selon l'invention se trouvent celles résultant de procédés non physiologiques, p. ex. de chirurgie ou de blessures corporelles, abrasions, lacérations, et de blessures résultant de brûlures (p.ex. une brûlure ou une blessure résultant d'une cryothérapie). Des ulcères, p. ex. des ulcères de jambe, des ulcères veineux et des ulcères gastriques, peuvent également être traités avec succès selon les méthodes de l'invention.

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