5-htp combination therapy

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/405 (2006.01) A61K 31/198 (2006.01) A61K 31/343 (2006.01) A61K 31/4525 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01)

Patent

CA 2655846

The present invention relates to combination therapies and pharmaceutical compositions comprising a combination of 5-hydroxytryptophan and a serotonin reuptake inhibitor. The present invention provides a pharmaceutical composition comprising (i) a serotonin reuptake inhibitor and (ii) 5-hydroxytrytophan. The present invention further provides a pharmaceutical composition comprising (i) 5-hydroxytryptophan in an amount ranging from about 1 mg to about 75 mg; and (ii) a serotonin reuptake inhibitor. The present invention also provides a pharmaceutical composition comprising (i) a subclinical dose of a serotonin reuptake inhibitor; and (ii) 5-hydroxytryptophan.

La présente invention concerne des polythérapies et des compositions pharmaceutiques renfermant une combinaison de 5-hydroxytryptophane et d'un inhibiteur de la réabsorption de la sérotonine. La présente invention concerne une composition pharmaceutique renfermant (i) un inhibiteur de la réabsorption de la sérotonine et (ii) du 5-hydroxytryptophane. La présente invention concerne en outre une composition pharmaceutique renfermant (i) du 5-hydroxytryptophane dans une quantité située dans la plage d'environ 1 mg à environ 75 mg ; et (ii) un inhibiteur de la réabsorption de la sérotonine. La présente invention concerne également une composition pharmaceutique renfermant (i) une dose subclinique d'un inhibiteur de la réabsorption de la sérotonine ; et (ii) du 5-hydroxytryptophane.

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