5-phenylthiazole derivatives and use as pi3 kinase inhibitors

Details 5-phenylthiazole derivatives and use as pi3 kinase inhibitors 5-phenylthiazole derivatives and use as pi3 kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 277/46 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61P 3/04 (2006.01) A61P 9/10 (2006.01) A61P 11/00 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01) A61P 37/08 (2006.01) C07D 277/48 (2006.01) C07D 417/10 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2477601

Compounds of Formula I in free or salt form, wherein R1,R2,R3,R4, and R5, have the meanings as indicated in the specification, are useful for treating diseases mediated by phosphatidylinositol 3-kinase. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.

L'invention porte sur des composés de formule (I) sous forme libre ou de sels. Dans ladite formule, R?1¿,R?2¿,R?3¿,R?4¿, et R?5¿, sont tels que définis dans la spécification et utilisables pour le traitement de maladies médiées par la phosphatidylinositol 3-kinase. L'invention porte également sur des préparations pharmaceutiques les contenant et sur leurs procédés de préparation.

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