C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/404 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2583287
The present invention relates to novel indole derivatives such as compounds of the formula (I): which possess antagonist potency at the 5-HT6 receptor and the use of such compounds or pharmaceutically acceptable salts or solvates thereof in the treatment of Alzheimer's disease and other CNS disorders.
La présente invention a trait à de nouveaux dérivés d'indole tels que des composés de formule (I), présentant une activité antagoniste vis-à-vis du récepteur 5-HT6 et l'utilisation de tels composés ou de sels ou solvates pharmaceutiquement acceptables de ceux-ci dans le traitement de la maladie d'Alzheimer ou d'autres troubles du système nerveux central.
Ahmed Mahmood
Johnson Christopher Norbert
Miller Neil Derek
Milner Peter Henry
Rivers Dean Andrew
Glaxo Group Limited
Gowling Lafleur Henderson Llp
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