6-(1-fluoroethyl)-5-iodo-4-aminopyrimidine compounds,...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/42 (2006.01) A01N 43/54 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2434230

6-(1-Fluoroethyl)-5-iodo-4-aminopyrimidine compounds represented by the general formula (1), a process for preparing the compounds, and pest controllers containing the same as the active ingredient: (1) wherein Ar is phenyl which may have one to three substituents selected from the group consisting of halogeno, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy, C1-4 haloalkoxy, and phenoxy, naphthyl, thienyl, indanyl, or 1,4-benzodioxan-6-yl; R is hydrogen or C1-4 alkyl; *1 represents an asymmetric carbon atom; and *2 represents an asymmetric carbon atom when R is C1-4 alkyl.

L'invention concerne des composés 6-(1-fluoroéthyl)-5-iodo-4-aminopyrimidine représentés par la formule générale (1):, un procédé de préparation de ces composés, et des antiparasitaires contenant ces composés en tant qu'ingrédients actifs. Dans cette formule Ar représente un groupe phényle qui peut porter de un à trois substituants choisis parmi le groupe comprenant un halogéno, un groupe C¿1-4? alkyle, C¿1-4 ?haloalkyle, C¿1-4 ?alcoxy, C¿1-4 ?haloalcoxy, et un groupe phénoxy, naphtyle, thiényle, indanyle, ou 1,4-benzodioxane-6-yle, R représente un hydrogène ou un groupe C¿1-4 ?alkyle, 1* représente un atome de carbone asymétrique et 2* représente un atome de carbone asymétrique lorsque R représente un groupe C¿1-4 ?alkyle.

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