6,7,8,9-tetrahydro-5h-1,4,7,10a-tetraaza-cyclohept[f]indene...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 487/14 (2006.01) A61K 31/519 (2006.01) A61P 3/00 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2743241

The present invention relates to compounds defined by formula (I), wherein the groups X, Y, W and R1 to R4 are defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are agonists of the 5-HT2C receptor, and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this receptor, such as metabolic and CNS-related disorders. Image

La présente invention concerne des composés définis par la formule (I), dans lesquels les groupes X, Y, W et R1 à R4 sont définis comme décrit dans la revendication 1, possédant une activité pharmacologique intéressante. En particulier, les composés sont des agonistes du récepteur de 5-HT2C, et sont donc adaptés pour le traitement et la prévention de maladies qui peuvent être influencées par linhibition de ce récepteur, telles que des troubles métaboliques et associés au SNC.

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