6(7)-amino-substituted quinoline-5,8-quinones for combating...

C - Chemistry – Metallurgy – 07 – D

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C07D 215/38 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 401/04 (2006.01) C07D 405/12 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2071566

Use of 6(7)-amino-substituted quinoline-5,8-quinones for combating endoparasites, new 6(7)-amino-substituted quinoline-5,8-quinones and processes for their preparation A b s t r a c t The present invention relates to the use of 6(7)-amino- substituted quinoline-5,8-quinones of the general formula (I) (I) Image in which R1 represents substituted C1-C6-alkyl or optionally substituted cycloalkylalkyl, cycloalkyl, aralkyl or aryl, substituents which may be mentioned being halogen, nitro, alkyl, alkylamino, aminoacyl, aryl, aryloxy, arylthio, aralkyl, halogenoalkyl, alkoxy, halogenoalkoxy, alkylthio, halogenoalkylthio, alkylsulphinyl, halogenoalkylsulphinyl, alkyl- sulphonyl or halogenoalkylsulphonyl, R2 represents hydrogen or alkyl, or R1 and R2, together with the adjacent N atom, represent a carbocyclic Le A 28 421 5-, 6- or 7-membered ring, which can optionally also be interrupted by O, N or S and is optionally substituted by C1-4-alkyl, R3 represents halogen or -S-R4 and R4 represents alkyl, for combating endoparasites in medicine and veterinary medicine, and to new 6(7)-amino-substituted quinoline- 5,8-quinones and their preparation. Le A 28 421

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