6-7-disubstituted...

Details 6-7-disubstituted... 6-7-disubstituted...

C - Chemistry, Metallurgy

07

D

167/211, 260/273

C07D 471/04 (2006.01) A61K 31/44 (2006.01) C07D 213/61 (2006.01) C07D 213/77 (2006.01) C07D 213/78 (2006.01) C07D 213/80 (2006.01)

Patent

CA 1339373

New 6,7-disubstituted-1-cyclopropyl-1,4-dihydro-4-oxo- 1,8-naphthyridine-3-carboxylic acids of the formula (I) (SEE FIG. I) in which X represents halogen or nitro and A represents (SEE FIG. II) or (SEE FIG. III) or halogen, wherein preferred values of R1 include hydrogen and lower alkyl, preferred values of R2 include hydrogen, methyl and phenyl, R3 represents hydrogen or methyl, and a preferred value of R4 is hydroxymethyl, are disclosed as well as their usefulness as anti-bacterial agents.

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