6-fluoro-1, 4-dihydro-4-oxo-7-substituted piperazinyl-...

Details 6-fluoro-1, 4-dihydro-4-oxo-7-substituted piperazinyl-... 6-fluoro-1, 4-dihydro-4-oxo-7-substituted piperazinyl-...

C - Chemistry, Metallurgy

07

D

260/266.3

C07D 401/04 (2006.01) C07D 215/56 (2006.01)

Patent

CA 1238638

ABSTRACT The invention is concerned with the novel piperazinyl-quinoline-3-carboxylic acid derivatives represented by formula (I): Image (I) or a pharmacologically-acceptable salt thereof, wherein R1 is a lower alkyl group having 1 to 4 carbon atoms, a vinyl group, a 2-fluoroethyl group or a 2-hydroxyethyl group; R2, R3 and R4 each is a hydrogen atom or a lower alkyl group having each 1 to 4 carbon atoms; R5 is a lower alkyl group having 1 to 4 carbon atoms and R6 is a hydrogen atom or a fluorine atom, a process for the preparation of them, and a pharmaceutical composition which contains these new compounds as active ingredients and can be used as the therapeutic agent against bacteria.

463652

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