7-{4-[2-(2,6-dichlor0-4-methylphenoxy)-ethoxy]phenyl}-3,9-di...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/08 (2006.01) A61K 31/504 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2595986

The invention relates to a novel 3,9-diazabicycl.alpha. [3.3. ljnonene derivative of formula (I) and the enantiomers thereof and the use thereof as active ingredients in the preparation of pharmaceutical compositions . The invention also concerns related aspects including pharmaceutical compositions containing at least one compound of formula (I) or (I') and especially their use as inhibitors of renin.(I).

L'invention concerne un nouveau dérivé 3,9-diazabicyclo[3.3.1]nonène représenté par la formule générale (I), ses énantiomères et leur utilisation comme ingrédients actifs dans la préparation de compositions pharmaceutiques. L'invention concerne également des aspects associés, y compris des compositions pharmaceutiques contenant au moins un composé représenté par la formule générale (I) ou (I') et en particulier leur utilisation comme inhibiteurs de la rénine.

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