7'-amino-naphthazarin antibiotic derivatives

Details 7'-amino-naphthazarin antibiotic derivatives 7'-amino-naphthazarin antibiotic derivatives

C - Chemistry, Metallurgy

07

D

C07D 493/20 (2006.01) A61K 31/365 (2006.01)

Patent

CA 2126216

2126216 9312115 PCTABS00022 New naphthazarin derivatives of formula (I) obtained by introducing in the 7' position of Purpuromycin or .gamma.-Rubromycin an amino or a monosubstituted amino group. The compounds of the invention show antibiotic activity against Gram positive and Gram negative microorganisms, fungi and protozoa and are suitable for the treatment of vaginal infections. Compounds of formula (IV) and (V) are also claimed.

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