C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/242.5
C07D 471/04 (2006.01)
Patent
CA 1233176
10-ALKYL-8,10 DIDEAZAMINOPTERINS Abstract 10-Alkyl-8,10-dideazaminopterins of the formula Image where R is alkyl of 1 to about 8 carbon atoms and their carboxylate and acid addition salts are described. These compounds exhibit antineoplastic activity that is similar to, but more effective than, methotrexate.
460707
de Graw Joseph I.
Kelly Lawrence F.
Sirotnak Francis M.
Gowling Lafleur Henderson Llp
Sri International
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