8-(3-amino-piperidin-1-yl)-7-(but-2-inyl)-xanthines,...

Details 8-(3-amino-piperidin-1-yl)-7-(but-2-inyl)-xanthines,... 8-(3-amino-piperidin-1-yl)-7-(but-2-inyl)-xanthines,...

C - Chemistry, Metallurgy

07

D

C07D 473/04 (2006.01) A61K 31/437 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2575751

The invention relates to substituted xanthines of general formula (I), wherein R1 and R2 have the meaning cited in claims 1 to 11. The invention also relates to the tautomers, enantiomers, diastereomers, mixtures and salts thereof, which have valuable pharmacological properties, especially an inhibiting action on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).

Nouvelles xanthines substituées de formule générale (I), dans laquelle R1 et R2 sont tels que définis dans les revendications 1 à 11, leurs tautomères, leurs énantiomères, leurs diastéréomères, leurs mélanges et leurs sels, qui possèdent des propriétés pharmacologiques précieuses, en particulier un effet inhibiteur sur l'activité de l'enzyme dipeptidylpeptidase-IV (DPP-IV).

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