C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 473/04 (2006.01) A61K 31/522 (2006.01) A61P 3/10 (2006.01) C07D 473/06 (2006.01) C07D 473/08 (2006.01)
Patent
CA 2496249
The invention relates to substituted xanthines of general formula (I) wherein R1 to R3 have the designations cited in patent claims 1 to 16, and to the tautomers, stereoisomers, mixtures, prodrugs and salts thereof, which have precious pharmacological properties, especially an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).
La présente invention concerne des xanthines substituées correspondant à la formule générale (I), dans laquelle les symboles R?1¿ à R?3¿ correspondent aux définitions données dans les revendications 1 à 16, ainsi que les tautomères, les stéréisomères, les mélanges, les promédicaments et les sels de ces xanthines, lesquels présentent de précieuses caractéristiques pharmacologiques, en particulier un effet inhibiteur sur l'activité de l'enzyme dipeptidylpeptidase-IV (DPP-IV).
Eckhardt Matthias
Himmelsbach Frank
Langkopf Elke
Lotz Ralf Richard Hermann
Maier Roland
Boehringer Ingelheim Pharma Gmbh & Co. Kg
Fetherstonhaugh & Co.
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