8-(3-biaryl)phenylquinoline phosphodiesterase-4-inhibitors

Details 8-(3-biaryl)phenylquinoline phosphodiesterase-4-inhibitors 8-(3-biaryl)phenylquinoline phosphodiesterase-4-inhibitors

C - Chemistry, Metallurgy

07

D

C07D 417/14 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01) C07D 215/12 (2006.01) C07D 401/10 (2006.01) C07D 401/14 (2006.01) C07D 409/10 (2006.01) C07D 413/10 (2006.01) C07D 413/14 (2006.01) C07D 417/10 (2006.01) C07D 471/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2523336

Novel substituted 8-phenylquinolines represented by Formula (I), wherein the phenyl group at the 8-position contains an aryl or heteroaryl substituent in the meta position, are PDE4 inhibitors.

L'invention concerne de nouvelles 8-phénylquinoléines substituées représentées par la formule (I), dans laquelle le groupe phényle en position 8 contient un substituant aryle ou hétéroaryle en position méta, lesquelles 8-phénylquinoléines sont des inhibiteurs de la PDE4.

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