A biological artificial nerve guide comprising a tissue...

A - Human Necessities – 61 – L

Patent

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Details

A61L 29/12 (2006.01) A61F 2/04 (2006.01) A61L 27/44 (2006.01)

Patent

CA 2634351

A biological nerve guide for implantation into a human body is made by a method that includes the steps of providing a natural animal tissue membrane, crosslinking and fixing the membrane, minimizing the antigens from the membrane, tanning the membrane, and coupling an active layer to the inner surface of the membrane, cutting the membrane into desired shape and size, positioning the cut of membrane onto a rod-shape mold so that the cut of membrane assumes a cylindrical configuration, and attaching a spiral support (2) to the outer surface of the cut of membrane.

La présente invention concerne un tube guide nerveux biologique conçu pour être implanté dans un corps humain. Ce tube guide nerveux est produit au moyen d'un procédé qui consiste à disposer d'une membrane de tissu animal naturel, à réticuler et à fixer la membrane, à minimiser les antigènes provenant de la membrane, à tanner la membrane, à coupler une couche active à la surface intérieure de la membrane, à découper la membrane à la forme et à la taille souhaitées, à placer la découpe de membrane sur un moule en forme de tige, de manière qu'elle adopte une configuration cylindrique, puis à appliquer un support en spirale (2) sur la surface extérieure de la découpe de membrane.

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