C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 231/12 (2006.01) C07C 237/46 (2006.01) C07C 231/22 (2006.01)
Patent
CA 2710594
This invention relates to an improved method for the synthesis of 5-acetamido- N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide ("Compound A"), an intermediate in the industrial preparation of non-ionic X-ray contrast agents. In particular, it relates to a continuous process of deacetylation of the acetylated hydroxyl group in 5-amino- N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide ("Compound B") followed by crystallisations, filtration, and washing of Compound A.
Askildsen Arne
Cervenka Jan
Hussain Khalid
Malthe-Sorenssen Didrik
Sorensen Thore Jarle
Fetherstonhaugh & Co.
Ge Healthcare As
LandOfFree
A continuous deacetylation and purification process in... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with A continuous deacetylation and purification process in..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A continuous deacetylation and purification process in... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1663853