A human t cell reactive feline protein (trfp) isolated from...

Details A human t cell reactive feline protein (trfp) isolated from... A human t cell reactive feline protein (trfp) isolated from...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 39/35 (2006.01) A61K 39/395 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 14/725 (2006.01) C07K 16/18 (2006.01) C12N 15/62 (2006.01) G01N 33/50 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2073045

A substantially pure, covalently linked human T cell reactive feline protein (TRFP) of approximately 40,000 MW has been isolated from vacuum bag extract obtained by affinity purification of house dust collected from several homes with cats; DNA encoding all or a portion of the TRFP or peptide; compositions containing such a protein or peptide or portions thereof; and an-tibodies reactive with the TRFP or peptide are disclosed. Also disclosed are recombinant TRFP or peptide; modified or mutated TRFP peptides; their use for diagnostic or therapeutic purposes.

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