A medical device and its use

Details A medical device and its use A medical device and its use

C - Chemistry, Metallurgy

03

C

C03C 4/00 (2006.01) A61K 33/00 (2006.01) A61L 15/18 (2006.01) A61L 15/44 (2006.01) A61P 17/02 (2006.01) C03C 3/076 (2006.01)

Patent

CA 2582832

The invention relates to a medical device comprising non-sintered bioactive glass particles or fibres having a diameter in the range 5 - 100 ~m, bioactive glass comprising SiO2, Na2O, CaO, K2O, MgO, B2O3 and P2O5, wherein the amount of SiO2 is 50-65 wt-% of the final total weight, Na2O is 5-26 wt-% of the final total weight, CaO is 10-25 wt-% of the final total weight, K2O is 0-15 wt-% of the final total weight, MgO is 0-6 wt-% of the final total weight, B2O3 is 0-4 wt-% of the final total weight, and P2O5 is 0-4 wt-% of the final total weight, provided that the total amount of Na2O and K2O is 10-30 wt-% of the final total weight. The device is essentially drug free. The invention also relates to the use of said composition for treating lesions associated with compromised or poor vascularisation and for preventing avascular fibrosis.

L'invention concerne un dispositif médical comprenant des particules ou des fibres de verre bioactif non fritté présentant un diamètre de 5-100 ?m, du verre bioactif comprenant du SiO2, du Na2O, du CaO, du K2O, du MgO, du B2O3 et du P2O5. Le SiO2 représente 50-65 % en poids du poids total final, le Na2O représente 5-26 % en poids du poids total final, le CaO représente 10-25 % en poids du poids total final, le K2O représente 0-15 % en poids du poids total final, le MgO représente 0-6 % en poids du poids total final, le B2O3 représente 0-4 % en poids du poids total final et le P2O5 représente 0-4 % en poids du poids total final, à la condition que la quantité totale de Na2O et de K2O soit de 10-30 % en poids du poids total final. Le dispositif selon l'invention est sensiblement exempt de médicaments. L'invention concerne également l'utilisation de cette composition pour traiter des lésions associées à une vascularisation affaiblie ou pauvre et pour prévenir la fibrose avasculaire.

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