A method for preparing liposome formulations with a...

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 9/127 (2006.01)

Patent

CA 2460209

The present invention provides a novel tool for designing a release profile of an active agent from a liposome in to which it is loaded. According to the invention, a method is provided for preparing a liposomal formulation for delivery of an active agent to a target, the release of said active agent from the liposome being designed to have a release profile in which the release is sustained for a time period to achieve an optimal effect of the active agent at said target, the method comprising preparing a liposomal formulation, wherein the liposome is loaded with said active agent and with a selected counter ion, the counter ion and the active agent interacting together to aggregate and/or to form a precipitate within the liposome, the counter ion being selected such that the release of the active agent from the liposome has said release profile.

La présente invention concerne un nouvel outil destiné à définir un profil de libération d'un agent actif à partir d'un liposome dans lequel cet agent est chargé. Selon l'invention, un procédé permet de préparer une formulation liposomale destinée à l'administration d'un agent actif au niveau d'une cible. La libération dudit agent actif à partir du liposome présente un profil impliquant une libération prolongée pendant une période donnée, d'où l'obtention d'un effet optimal de l'agent actif au niveau de cette cible. Ledit procédé consiste à préparer une formulation liposomale, le liposome étant chargé de cet agent actif et d'un contre-ion sélectionné, le contre-ion et l'agent actif interagissant ensemble de façon à s'agréger et/ou à former un précipité dans le liposome, ledit contre-ion étant sélectionné de sorte que la libération de l'agent actif à partir du liposome présente le profil susmentionné.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

A method for preparing liposome formulations with a... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with A method for preparing liposome formulations with a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A method for preparing liposome formulations with a... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1821020

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.