A method for providing and analyzing an animal population...

A - Human Necessities – 01 – K

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A01K 29/00 (2006.01) A01K 1/03 (2006.01) A01K 67/02 (2006.01)

Patent

CA 2615892

The present invention relates to a method for providing an animal population having an essentially identical metabolome comprising compiling an animal population being of essentially the same age, keeping said animal population for a time period sufficient for acclimatization under the following housing conditions: (i) constant temperature, (ii) constant humidity, (iii) physical separation of the animals of the animal population, (iv) feeding ad libitum, wherein the food to be fed is essentially free of chemical or micro- bial contaminance, (v) drinking libitum, wherein the drinking liquid is essentially free of chemical or microbial contaminance, (vi) constant illumination period, and providing the animal population after said time period. Further, the present invention relates to methods for the identification of a compound which effects the metabolome of an animal, or methods for the identification of a marker for such compounds. Moreover, the present invention encompasses methods for the identification of such compounds or markers thereof comprising metabolically analyzing a sample from at least one animal of an animal population.

La présente invention concerne un procédé de fourniture d~une population animale ayant un métabolome essentiellement identique consistant à compiler une population animale ayant essentiellement le même âge, à conserver ladite population animale pour une période suffisante pour une acclimatation dans les conditions de logement suivantes : (i) température constante, (ii) humidité constante, (iii) séparation physique des animaux de la population animale, (iv) avec alimentation ad libitum, où les aliments à donner sont essentiellement exempts de contamination chimique ou microbienne, (v) avec boisson ad libitum, où le liquide de boisson est essentiellement exempt de contamination chimique ou microbienne, (vi) période d~éclairage constant, et à fournir la population animale après ladite période. Par ailleurs, la présente invention concerne des procédés d~identification d~un composé réalisant le métabolome d~un animal, ou des procédés d~identification d~un marqueur pour lesdits composés. De plus, la présente invention englobe des procédés d~identification de tels composés ou marqueurs de ceux-ci consistant en une analyse métabolique d~un échantillon d~au moins un animal parmi une population animale.

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