A method of preventing depletion of non-autologous...

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A01K 67/027 (2006.01) A61K 31/66 (2006.01) A61K 35/28 (2006.01) A61K 35/54 (2006.01)

Patent

CA 2174729

The invention provides methods for preventing depletion of non-antologous hematopoietic cells by decreasing the level of endogenous macrophages. Animal model systems using the methods are also provided as are methods of treatment using non-autologous hematopoetic cells.

L'invention se rapporte à des procédés de prévention de la déplétion des cellules hématopoïétiques non autologues, qui consistent à réduire le taux des macrophages endogènes. L'invention se rapporte également à des systèmes de modèles animaux utilisant les procédés, et aux procédés de traitement mettant en oeuvre les cellules hématopoïétiques non autologues.

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