A new extended release oral dosage form

Details A new extended release oral dosage form A new extended release oral dosage form

A - Human Necessities

61

K

A61K 9/22 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61P 25/00 (2006.01) A61P 25/04 (2006.01)

Patent

CA 2457341

The present invention relates to a new extended release oral dosage form of a good soluble pharmaceutically active substance. More particularly, the invention relates to an extended release oral dosage form that provides a defined blood concentration profile having no rapid initial rise in blood plasma concentration of the good soluble active substance when administered at low dose. The invention further relates to processes for preparing said dosage form, the use of said dosage form and a method of prevention and/or treatment of CNS disorders and related medical disturbances using said dosage form.

La présente invention concerne une nouvelle forme posologique orale à libération prolongée d'une substance pharmaceutiquement tolérable à bonne solubilité. L'invention concerne notamment une forme posologique orale à libération prolongée permettant d'obtenir un profil de concentration sanguine défini dépourvu d'augmentation initiale rapide de la concentration du plasma sanguin de la substance active à bonne solubilité lorsqu'elle est administrée à faible dose. L'invention concerne des procédés de préparation de cette forme posologique, l'utilisation de cette forme posologique et un procédé de prévention et/ou de traitement des troubles du système central nerveux et des perturbations médicales associées à l'aide de cette forme posologique.

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