C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/705 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2423954
The present invention describes a newly discovered human G-protein coupled receptor and its encoding polynucleotide. Also described are expression vectors, host cells, agonists, antagonists, antisense molecules, and antibodies associated with the polynucleotide and/or polypeptide of the present invention. In addition, methods for treating, diagnosing, preventing and screening for disorders associated with aberrant cell growth and those related to the small intestine and colon are illustrated.
La présente invention concerne un nouveau récepteur couplé à la protéine G humaine et son polynucléotide codant. L'invention concerne également des vecteurs d'expression, des agonistes, des antagonistes, des molécules antisens et des anticorps associés au polynucléotide et/ou au polypeptide de la présente invention. Elle se rapporte en outre à des méthodes destinées à traiter, diagnostiquer, prévenir et dépister les troubles associés à la prolifération cellulaire aberrante et les affections liées à l'intestin grêle et au côlon.
Barber Lauren
Cacace Angela
Feder John N.
Hawken Donald R.
Kornacker Michael G.
Bristol-Myers Squibb Pharma Company
Gowling Lafleur Henderson Llp
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