A process for producing solid dosage forms

A - Human Necessities – 61 – K

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A61K 9/20 (2006.01) A61J 3/06 (2006.01) A61K 31/16 (2006.01) A61K 31/192 (2006.01) A61K 31/275 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) A61K 31/60 (2006.01) B29B 9/00 (2006.01)

Patent

CA 2284314

A process for producing solid dosage forms, in which (i) a plastic mixture of at least one pharmacologically acceptable polymeric binder with a K value of more than 75, at least one pharmaceutical active ingredient and, where appropriate, conventional pharmaceutical additives is prepared and (ii) the plastic mixture is shaped to the required dosage form, with step (i) being carried out under conditions of temperature and shear energy input such that the reduction in molecular weight of the polymeric binder, expressed as the difference in the K value, is less than 15 is described.

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