A process for purifying lovastatin and simvastatin with...

Details A process for purifying lovastatin and simvastatin with... A process for purifying lovastatin and simvastatin with...

C - Chemistry, Metallurgy

07

D

C07D 311/00 (2006.01) C07C 69/74 (2006.01) C07D 309/30 (2006.01)

Patent

CA 2402061

A process reducing the levels of dimeric impurities in a statin to less than 0.08 % by treatment of a statin containing more than 0.08 % dimeric impurities with a mild base in a suitable solvent mixture.

L'invention concerne un procédé de réduction à moins de 0,08 % de la teneur en impuretés dimères dans une statine, par le traitement d'une statine contenant plus de 0,08 % d'impuretés dimères, à l'aide d'une base douce dans un mélange solvant approprié.

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