A process for the preparation of 13-cis-retinoic acid

Details A process for the preparation of 13-cis-retinoic acid A process for the preparation of 13-cis-retinoic acid

C - Chemistry, Metallurgy

07

C

C07C 403/20 (2006.01) C07C 51/353 (2006.01) C07C 57/03 (2006.01)

Patent

CA 2272439

A process for the synthesis of 13-cis-retinoic acid of Formula I (see formula I) with high purity and stability, without using heavy metals at any steps, starting from vinyl-beta-ionol prepared from ionone and vinyl magnesium halides.

Divulgation d'un procédé de synthèse de l'acide 13-cis-rétinoïque de formule I (voir la formule I) très stable et d'une grande pureté, sans recours à des métaux lourds à aucune étape et à partir de vinyl- -ionol préparé lui-même à partir d'ionone et d'halogénures de vinylmagnésium.

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