C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 333/08 (2006.01) A61K 31/18 (2006.01) C07C 257/18 (2006.01) C07C 311/16 (2006.01) C07C 317/44 (2006.01) C07D 211/46 (2006.01) C07D 213/30 (2006.01) C07D 271/06 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2417427
The invention relates to novel compounds of formula (I) wherein R, R1 and R2 have the designation cited in patent claim 1. Said compounds are inhibitors of the coagulation factors Xa and VIIa, and can be used to treat thromboses, myocardial infarction, arteriosclerosis, inflammation, apoplexy, angina pectoris, restenosis after angioplasty, intermittent claudication, tumours, tumour diseases and/or tumour metastases.
Nouveaux composés de formule (I) dans laquelle R, R?1¿ et R?2¿ possèdent la signification figurant à la revendication 1, qui sont des inhibiteurs du facteur de coagulation Xa et VIIa et peuvent être utilisés pour traiter les thromboses, l'infarctus du myocarde, l'artériosclérose, les inflammations, l'apoplexie, l'angine de poitrine, la resténose après angioplastie, la claudication intermittente, les tumeurs, les maladies tumorales et / ou les métastases.
Barnes Christopher
Dorsch Dieter
Gleitz Johannes
Juraszyk Horst
Mederski Werner
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
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