C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/06 (2006.01) A61K 31/35 (2006.01) A61K 31/38 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) C07D 405/06 (2006.01) C07D 407/06 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2091763
2091763 9206092 PCTABS00011 Retinoid-like activity is exhibited by compounds of formula (I) where X is S, O or NR'; where R' is hydrogen or lower alkyl; R1, R2 and R3 are hydrogen or lower alkyl; R4 and R5 are hydrogen or lower alkyl with the proviso that R4 and R5 cannot both be hydrogen, A is pyridyl, thienyl, furyl, pyridazinyl, pirimidinyl, pyrazinyl, thiazolyl or oxazolyl; n is 0 - 5, and B is H, -COOH or a pharmaceutically acceptable salt, ester or amide thereof, -CH2OH or an ether or ester derivative, or -CHO or an acetal derivative, or -COR1 or a ketal derivative where R1 is -(CH2)mCH3 where m is 0 - 4, or a pharmaceutically acceptable salt thereof.
Allergan Inc.
Gowling Lafleur Henderson Llp
LandOfFree
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