Activation and expansion of t cells

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/0783 (2010.01) A61K 35/14 (2006.01) A61P 35/00 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2514052

The present invention relates generally to methods for activating and expanding T cells, and more particularly, to a novel method to activate and/or stimulate T cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.

La présente invention concerne globalement des méthodes d'activation et de multiplication de cellules et plus particulièrement une nouvelle méthode d'activation et/ou de stimulation de cellules qui maximise la croissance de telles cellules en vue d'atteindre des densités extrêmement hautes. Dans les diverses formes de réalisation, les cellules sont activées et multipliées à des densités très élevées en un temps très court. Dans certaines formes de réalisation, les cellules sont activées et multipliées jusqu'à atteindre des nombres de cellules très élevés en une courte période de temps. Des compositions de cellules activées et multipliées au moyen des méthodes selon l'invention sont également présentées.

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