Activation of hypoxia-inducible gene expression

Details Activation of hypoxia-inducible gene expression Activation of hypoxia-inducible gene expression

A - Human Necessities

61

K

A61K 31/19 (2006.01)

Patent

CA 2544499

The present invention relates to the elucidation of specific molecular features of endogenous 2-oxoacid molecules and their derivatives for activating hypoxia-inducible e gene expression by inactivating hypoxia- inducible factor hydroxylating enzymes. This invention identifies agents that can be used to induce tissue vascularization, treat anemias, induce tolerance to stroke and heart attacks, improve tissue healing and improve organ transplantation.

L'invention concerne l'élucidation de caractéristiques moléculaires spécifiques de molécules de 2-oxoacide endogènes et de dérivés de celles-ci, aux fins d'activation d'expression génique pouvant être induite par hypoxie, par inactivation d'enzymes hydroxylantes du facteur pouvant induire l'hypoxie. L'élucidation selon l'invention permet d'identifier des agents pouvant être utilisés pour induire la vascularisation des tissus, traiter des anémies, induire une tolérance aux accidents vasculaires et crises cardiaques, améliorer la guérison des tissus et améliorer la transplantation d'organe.

Affiliated with

Also associated with

Rating

Activation of hypoxia-inducible gene expression does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Activation of hypoxia-inducible gene expression, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Activation of hypoxia-inducible gene expression will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1762604