A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
128/104
A61M 31/00 (2006.01) A61K 9/20 (2006.01) A61K 9/70 (2006.01)
Patent
CA 1227982
-1- ABSTRACT OF THE DISCLOSURE The release pattern of a dispersion type active agent dispenser can be improved by forming the device from a depleted zone containing the agent at a concentration no greater than the saturation and a non-depleted zone containing the agent dispersed in the matrix at a uniform concentration greater than saturation. The depleted zone is disposed between the surface through which the agent is to be dispensed and at least a substantial portion of the non-depleted zone with the inter- face therebetween disposed at a non-uniform distance from the releasing surface. Certain embodiments are particularly useful for the transdermal administration of drugs.
455103
Wong Patrick S.l.
Zaffaroni Alejandro
Alza Corporation
Smart & Biggar
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