Acyltryptophanols for fertility control

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 209/14 (2006.01) A61K 31/4045 (2006.01) A61K 31/4709 (2006.01) A61K 31/495 (2006.01) A61P 15/08 (2006.01) C07C 63/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2618888

The present patent application relates to acyltryptophanols of the general formula I, in which Q, X, Y, W, R1, R2, R3, R4, R5, R8 have the meanings stated in the description. The compounds according to the invention are effective FSH antagonists and can be used for example for fertility control in men or in women, or for the prevention and/or treatment of osteoporosis.

L'invention concerne des acyltryptophanols représentés par la formule (I), dans laquelle Q, X, Y, W, R1, R2, R3, R4, R5, R8 ont les significations définies dans la description. Les composés de l'invention sont des antagonistes FSH efficaces et peuvent être utilisés, par exemple, pour réguler la fécondité chez les hommes ou chez les femmes ou pour prévenir et/ou traiter l'ostéoporose.

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