B - Operations – Transporting – 01 – J
Patent
B - Operations, Transporting
01
J
B01J 20/22 (2006.01) A61M 1/36 (2006.01) B01J 20/26 (2006.01) A61K 31/7068 (2006.01)
Patent
CA 2487600
An object of this invention is to provide an adsorbent for immunosuppressive substance, which adsorbent can highly efficiently and selectively adsorb an excessive immunosuppressive substance directly from the body fluid, can carry out extracorporeal perfusion safely and can be utilized in treatment of cancer. Such an excessive immunosuppressive substance may be involved in growth of cancer cells. An adsorbent for immunosuppressive substance of the invention includes a water-insoluble carrier and a hydrophilic amino group immobilized to the water-insoluble carrier. An extracorporeal perfusion column of the invention contains the adsorbent of the invention. A method for treating cancer of the invention carries out extracorporeal perfusion using the extracorporeal perfusion column of the invention.
L'invention concerne un adsorbant d'une substance immunosuppressive, capable d'adsorber sélectivement l'excès de substances immunosuppressives, excès considéré comme étant associé avec la multiplication de cellules carcinomiques, directement à partir de l'humeur, avec un rendement élevé, et apte à une circulation extracorporelle sûre, ledit adsorbant de substance immunosuppressive étant utilisé pour le traitement du cancer. L'invention concerne en particulier un adsorbant d'une substance immunosuppressive, caractérisé en ce qu'il comprend un support insoluble dans l'eau et des groupes amino hydrophiles fixés à ce support. En outre, l'invention concerne une colonne de circulation extracorporelle caractérisée en ce qu'elle est garnie de l'adsorbant précité. De plus, l'invention concerne un procédé de traitement du cancer caractérisé en ce que ladite circulation extracorporelle est effectuée au moyen de la colonne de circulation extracorporelle précitée.
Matsunase Takeo
Shimagaki Masaaki
Teramoto Kazuo
Ueda Yuji
Watanabe Koji
Smart & Biggar
Toray Industries Inc.
LandOfFree
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