Agent for inhibition of cytokine production and agent for...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/425 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) A61K 31/506 (2006.01)

Patent

CA 2265746

The present invention provides an agent for inhibiting cytokine production or cell adhesion, comprising at least one compound selected from the group consisting of thiazole derivatives represented by general formula (1), wherein R1 is a phenyl group which may have a lower alkoxy group(s) as a substituent(s) on the phenyl ring, and R2 is a group represented by general formula (2), wherein R3s, which may be the same or different, are each a carboxyl group, a lower alkoxy group or the like, and salts thereof.

Cette invention se rapporte à une agent inhibant la production de cytokine ou l'adhésion cellulaire qui comprend au moins un composé choisi dans le groupe constitué par des dérivés de thiazole représentés par la formule générale (1) où R<1> représente un groupe phényle pouvant comportant un ou plusieurs groupes alcoxy inférieur comme substituant(s) sur le cycle phényle; et R<2> représente un groupe représenté par la formule générale (2) où les éléments R<3>, qui peuvent être identiques ou différents, représentent chacun un groupe carboxyle, un groupe alcoxy inférieur ou similaire, cette invention se rapportant également à des sels d'un tel composé.

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