Alkoxy indolinone based protein kinase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 403/06 (2006.01)

Patent

CA 2621809

Alkoxy indolinone based acid and amide derivatives have enhanced and unexpected drug properties as inhibitors of protein kinases and are useful in treating disorders related to abnormal protein kinase activities such as cancer.

L'invention concerne des dérivés d'amide et d'acide à base d'alkoxy indolinone présentant des propriétés médicamenteuses améliorées inattendues, en tant qu'inhibiteurs de protéines kinases. Ces dérivés sont utiles pour traiter des troubles associés à des activités anormales de protéines kinases, notamment le cancer.

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