Allelic variation of the serotonin 5ht2c receptor

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2199470

Isolated DNA encoding the serotonin 5HT2C receptor with serine at amino acid position 23, antibody specific to such a variant receptor and the variant receptor protein itself are used in methods for detecting the presence of an allelic variant of the serotonin 5HT2C gene or receptor.

L'invention porte sur un ADN isolé codant le récepteur 5HT¿2C? de la sérotonine, ledit récepteur présentant une sérine à la position d'acide aminé 23, sur un anticorps spécifique d'une telle variante du récepteur, sur la variante elle-même du récepteur protéinique, ainsi que sur des procédés de détection de la présence d'une variante allélique du gène ou du récepteur 5HT¿2C? de la sérotonine.

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