Alpha-9 integrin antagonists and anti-inflammatory...

Details Alpha-9 integrin antagonists and anti-inflammatory... Alpha-9 integrin antagonists and anti-inflammatory...

A - Human Necessities

61

K

A61K 31/54 (2006.01) A61K 31/198 (2006.01) A61K 31/401 (2006.01) A61K 31/426 (2006.01) A61K 31/496 (2006.01) A61K 45/00 (2006.01) C07K 5/00 (2006.01) C07K 5/06 (2006.01) C07K 5/078 (2006.01)

Patent

CA 2267175

The disclosed invention includes pharma-ceutical compositions and methods for treating in-flammatory conditions, particularly those that are characterized by increased binding of alpha-9 in-tegrin to one or more of its ligands. Also dis-closed are methods for selecting compounds for use in such compositions and methods.

La présente invention concerne des compositions pharmaceutiques et des méthodes de traitement d'états inflammatoires, en particulier ceux qui se caractérisent par une liaison accrue de l'intégrine alpha-9 sur un ou plusieurs de ses ligands. L'invention concerne également des procédés permettant de sélectionner des composés à utiliser dans de telles compositions et méthodes.

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